College football pick 'em

College football fans had been looking forward to this weekend for weeks, as it would feature six games between teams ranked in the AP top 25.

Including several crucial conference matchups that could have a direct impact on the outcome of the national title race.

What can we anticipate from the games this week? This week, we consult FPI to help inform our picks for the most pivotal games.

The Football Power Index (FPI) is a statistical model and ranking system for predicting the outcomes of collegiate football games.

Developed by football statisticians, it factors in a team's current record, its opponents' records, the team's overall talent.

Wolverines head coach Jim Harbaugh is back at the helm as the team prepares for its Big Ten debut against a 3-0 Knights squad .

The computer models and oddsmakers agree that this game will be close, as Clemson will be trying to avoid falling to 2-2 against a Seminole.

The Sooners, who are second in the Big 12 in scoring at 56 points per game, will get to show off their skills against a Cincinnati club.

It's not that Oregon shouldn't be favored at home, but the score is shocking given how strong Colorado has played thus far.

 Even though the Buffs have some elite talent players and Travis Hunter's absence will hurt, the Ducks are formidable on both ends of the field.